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The sodium nitrite had reacted with dimethylamine in the fish and produced dimethylnitrosamine.
Dimethylamine undergoes nitrosation under weak acid conditions to give dimethylnitrosamine.
In 1956, two British scientists, John Barnes and Peter Magee, reported that dimethylnitrosamine produced liver tumours in rats.
On the effects of Amygdalin (Vitamin B-17) in Cancer Evaluation in rats administered Dimethylnitrosamine.
Some of these have marked irritant properties and some 60, including benzo(a)pyrene and dimethylnitrosamine, have been shown to cause cancer when applied to living tissue.
Unbeknownst to the parties, the sodium nitrite preservative used in the Norwegian herring meal produced a substance, dimethylnitrosamine (DMNA), toxic to many animals, highly so to mink.
N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is a semi-volatile organic chemical that is highly toxic and is a suspected human carcinogen.
Bosan WS, Shank RC, MacEwen JD, et al.: Methylation of DNA guanine during the course of induction of liver cancer in hamsters by hydrazine or dimethylnitrosamine.