In rare cases, basal cell carcinoma may develop in a dermatofibroma.

They are also found in dermatofibroma.

Similar to a dermatofibroma, it is believed to be a reparative process secondary to trauma, which is frequently not remembered.

It is associated with dermatofibroma.

Epithelioid cell histiocytoma is a rare skin condition that is considered to be a variant of a dermatofibroma.

Deep penetrating dermatofibroma may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.

The hard fibroma (fibroma durum) consists of many fibres and few cells, e.g. in skin it is called dermatofibroma (fibroma simplex or nodulus cutaneous).

The clinical differential diagnosis includes: dermatofibroma, inflamed seborrheic keratosis, pyogenic granuloma, basal cell carcinoma, squamous cell carcinoma, verruca vulgaris, psoriatic plaque, and melanoma.