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Vaccinov was the name given to the first Russian to receive the cowpox vaccine against smallpox.
He attempted to maintain a monopoly over the cowpox vaccine, for both financial reasons and to protect the vaccine from incompetent or fraudulent physicians.
Dr. Saugrain was the first physician west of the Mississippi River to use the Jenner cowpox vaccine to prevent smallpox, beginning in 1809.
The authors of the study suggested that the findings might help in developing an AIDS vaccine, perhaps one modeled after the cowpox vaccine that was used to protect against smallpox.
In the years following 1770, at least five investigators in England and Germany (Sevel, Jensen, Jesty 1774, Rendell, Plett 1791) successfully tested a cowpox vaccine in humans against smallpox.
In 1849 he instituted the practice of delivering fresh cowpox vaccine from Batavia in the Dutch East Indies to the Japanese port of Nagasaki, thus creating a sharp reduction of smallpox in Japan.