connectome

The map produced by such a project is called a connectome.

A connectome is a comprehensive map of neural connections in the brain.

EyeWire is a game for finding the connectome of the retina.

Origin and usage of the term "connectome"

For example, connectome maps can be used to inform computational models of whole-brain dynamics.

Most other representations of the connectome use 3 dimensions, and therefore require an interactive graphical user interface.

The term "connectome" is used primarily in scientific efforts to capture, map, and understand the organization of neural interactions within the brain.

In fact, the connectome can evidently support a great number of variable dynamic states, depending on current sensory inputs, global brain state, learning and development.

Established methods of brain research, such as axonal tracing, provided early avenues for building connectome data sets.

Indeed, the foundation of human cognition lies in the pattern of dynamic interactions shaped by the connectome.

It is then possible to trace each motor axon and its synaptic contacts to construct a complete connectome of the muscle.

A "mesoscale" connectome corresponds to a spatial resolution of hundreds of micrometers.

EyeWire users help scientists trace neurons through the retina, with the goal of creating a full retinal connectome.

Mapping the connectome at the "microscale" (micrometer resolution) means building a complete map of the neural systems, neuron-by-neuron.

EM reconstruction was successfully used for the compilation of the C. elegans connectome (White et al., 1986).

In 2012, a Citizen science project called EyeWire began attempting to crowdsource the mapping of the connectome through an interactive game.

A few related -ome words already existed - such as biome, rhizome and, more recently, connectome - forming a vocabulary into which genome fits systematically.

Mapping the connectome at the cellular level in vertebrates currently requires post-mortem microscopic analysis of limited portions of brain tissue.

In the hermaphrodite, this comprises 302 neurons whose pattern of connectivity, or "connectome", has been completely mapped and shown to be a small-world network.

In their 2005 paper, The Human Connectome, a structural description of the human brain, Sporns et al. wrote:

We propose to call this dataset the human "connectome," and we argue that it is fundamentally important in cognitive neuroscience and neuropsychology.

By comparing diseased connectome and healthy connectomes, we should gain insight into certain psychopathologies, such as neuropathic pain, and potential therapies for them.

The development of FieldTrip is currently supported by funding from the BrainGain and the Human Connectome projects.

Accurate parcellation allows each node in the macroscale connectome to be more informative by associating it with a distinct connectivity pattern and functional profile.

The receptorome is a concept analogue to the genome and proteome but also to other sets of structural or functional units such as the proteasome and connectome.