Congenital insensitivity to pain with anhidrosis may be misdiagnosed for leprosy, based on similar symptoms of severe injuries to the hands and feet.

Mutations in this gene have been associated with congenital insensitivity to pain with anhidrosis, self-mutilating behavior, mental retardation and cancer.

In a Bedouin tent camp south of Beersheba, Omar, 11, lives with an especially rare disorder known as "congenital insensitivity to pain with anhidrosis."

Congenital insensitivity to pain with anhidrosis (HSAN Type IV), a rare neural disorder, in which the patient does not feel pain, heat or cold.

Most people with congenital insensitivity to pain have one of five hereditary sensory and autonomic neuropathies (which includes familial dysautonomia and congenital insensitivity to pain with anhidrosis).

Included were a "Muscular Dystrophy Child", a "Family who has multiple children w/ Down Syndrome (either adopted or biological)" and a child with Congenital insensitivity to pain with anhidrosis.