Imerslund-Gräsbeck syndrome , IGS (skrót)
congenital cobalamin malabsorption

He is best known for his contribution to the identification and naming of the Imerslund-Gräsbeck syndrome.

Olga Imerslund (9 April 1907 - 23 August 1987) was a renowned Norwegian pediatrician best known for her contribution to identification and naming of the Imerslund-Gräsbeck syndrome.

Autosomal recessive mutations in both component of Cubam (AMN, and cubilin) is responsible for Imerslund-Gräsbeck syndrome, which manifests as macrycytic, megaloblastic anemia.

To understand the basic pathophysiology of Imerslund-Gräsbeck syndrome, it is imperative to understand the absorption of vitamin B. The following lists principal events that lead to absorption of vitamin B along the GI tract: