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These changes have a high impact on the reinstatement conditioned place preference.
There are numerous advantages of the conditioned place preference and aversion protocol.
The specific dosages administered established if the conditioned place preference was blocked.
The exact dosages that produced a conditioned place preference varied across studies.
This is called conditioned place preference and is seen after injection of cocaine.
There are two main modes of action for which reinstatement is often tested in the conditioned place preference paradigm.
For example, morphine, heroin, and fentanyl have been shown to produce conditioned place preference.
Evidence debates the conditioned place preference of diazepam.
Without active Elk1, c-fos production and cocaine-induced conditioned place preference are shown to be blocked.
The conditioned place preference protocol makes use of an apparatus that contains two or more compartments or areas.
The conditioned place preference and aversion protocol is subject to several disadvantages and limitations.
It was found that MK-801 administration elicited conditioned place preference in animals, again demonstrating its reinforcing properties.
Conditioned place preference involves three phases: habituation, conditioning and preference testing.
Lesion studies have been preformed to measure the effects certain areas have on the conditioned place preference of cocaine.
Mice lacking the mu opioid receptor exhibited a lack of conditioned place preference.
Apomorphine displays a conditioned place preference when injected subcutaneous within a range of 5-10 mg/kg.
It has demonstrated a conditioned place preference at 5 mg/kg through intravenous and intraperitoneal injections.
No conditioned place preference was found in knockout mice lacking serotonin receptor 5-HT.
Even though the conditioned place preference of methylphenidate appears to show it has an addictive property, it does not display the same effects in humans.
In the case of CPP, when drugs are used to establish conditioned place preference, this is called drug priming.
A conditioned place preference was demonstrated in rats with an intravenous injection of 0.25-0.5 mg/kg of cocaine.
In addition to conditioned placed preference, animal testing using self-administration procedures have also been used to examine potential causes of relapse in humans.
Studies show the conditioned place preference of cocaine appears to be blocked by a variety of drugs including mecamylamine, scopolamine, and caffeine.
Knockouts of CB cannabinoid receptor demonstrated a lack of conditioned place preference.
Studies that have examined intraperitoneal injections in rats and mice have shown a conditioned place preference around 1 mg/kg.