chronic polyarthritis

Sander O, Herborn G, Rau R. [Is H15 (resin extract of Boswellia serrata, "incense") a useful supplement to established drug therapy of chronic polyarthritis?

In 1991, George Kollias' group was first to provide in vivo, proof of principle studies, on deregulated TNF production being causal to the development of chronic polyarthritis in a transgenic animal model, and for showing originally that anti-huTNF antibody treatment was efficacious in treating the modeled disease.