There is no associated inflammatory response and no cellular atypia.

When cellular atypia is noted, a pathologist might indicate that the entire lesion should be removed.

The 'further back' in an already specialised, differentiated cell's lineage, the more problematic cellular atypia is likely to be.

An initial small punch biopsy of a melanoma might say "severe cellular atypia, recommend wider excision".

A malignant blue nevus is a cutaneous condition characterized by a sheet-like growth pattern, mitoses, necrosis, and cellular atypia.

While one section of the tumor might show benign melanocytic nevus, another section might show features concerning of severe cellular atypia.

Cystadenocarcinomas (malignant tumors) contain a more solid growth pattern with the hallmarks of malignancy: cellular atypia and stratification, loss of the normal architecture of the tissue, and necrosis.

Dooley WC, Ljung BM, Veronesi U, et al.: Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.

For example, already differentiated, specialised cells such as epithelia displaying "cellular atypia" are far less likely to become problematic [cancerous/ malignant] than are myeloid progeniotor cells of the immune system.

When they become malignant, there is usually a morphologically apparent focus from within the large lesion that has crowding, irregular growth pattern and marked cellular atypia that is strikingly different from the surrounding cells.

The word dyspalsia generally means "abnormal growth", and specifically in the context of oral red or white lesions refers to microscopic changes ("cellular atypia") in the mucosa that indicate a risk of malignant transformation.