biomechanical changes

He said these abnormalities might cause biomechanical changes that in turn weaken the cartilage around the bones.

Although some of the biochemical changes are reversible after the blood is transfused, the biomechanical changes are less so, and rejuvenation products are not yet able to adequately reverse this phenomenon.

Insufficient transfusion efficacy can result from red blood cell (RBC) blood product units damaged by so-called storage lesion - a set of biochemical and biomechanical changes which occur during storage.