Such tablets are retained in the stomach for a longer period of time and thereby improve the bioavailability of drugs.

The method should be able to yield information about why tablets dissolve unequally before or after meals, which may be important for the bioavailability of drugs.

The modulation of P-glycoprotein activity may result in altered absorption and bioavailability of drugs that are P-glycoprotein substrates.

Nanoparticles have been explored as a delivery system for various drugs and an improvement of the oral bioavailability of drugs with poor absorption characteristics has been reported; the pathways of absorption and the efficiency were affected by reduction of particle size.