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Secretin also has an amidated carboxyl-terminal amino acid which is valine.
Both the amidated C-terminus and the disulfide bridge are necessary for the full biological activity of amylin.
Amidated pectin is a modified form of pectin.
With low-ester pectins and amidated pectins less sugar is needed, so that diet products can be made.
Glyoxylate is the byproduct of the amidation process in biosynthesis of several amidated peptides.
Because it is an amidated peptide, like many neuropeptides, it is believed to be responsible for the anorectic effect.
GnRH is a C-terminal amidated decapeptide processed from a larger precursor protein.
We conclude therefore that progastrin is frequently produced by colorectal cancers but the phenotype for processing to amidated products is usually not well developed.
Amidated pectins behave like low-ester pectins but need less calcium and are more tolerant of excess calcium.
Also, gels from amidated pectin are thermo-reversible; they can be heated and after cooling solidify again, whereas conventional pectin-gels will afterwards remain liquid.
The post translational processing mechanisms that convert progastrin to amidated peptides are known to operate at the post Golgi level on this pathway.
The κ- Hefutoxin1 consists of 22 residues and with an amidated C terminus and is the shortest scorpion toxin reported so far.
An ET analog with only the Cys1–Cys15 disulfide bond and an amidated carboxy terminus had no significant activity in the pulmonary vascular bed.
For the most part, the biologically active forms of gastrin - that is, C-terminally amidated peptides, were found in much lower concentrations than other progastrin derived peptides.
Our data suggest that the biologically active amidated peptides that are potential mediators of these actions cannot be more than a small proportion of the total progastrin produced.
In Europe, pectins are differentiated into the E numbers E440(i) for non-amidated pectins and E440(ii) for amidated pectins.
This distinction is crucial in the present context, because it appears that material resulting from endopeptidase cleavage is rather commonly encountered whereas material generated at the later stages (Gly-extended and amidated products) is less common.
Calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin are structurally related polypeptides characterized by a six or seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus.
There are three major steps in the production of amidated gastrins from progastrin: endopeptidase cleavage, carboxypeptidase trimming of Arg residues and conversion of Gly-extended to amidated products.
Marounek, M., Volek, Z., Synytsya, A., and Copikova, J. Effect of pectin and amidated pectin on cholesterol homeostasis and caecal metabolism in rats fed a high-cholesterol diet.
They are derivatives of the eurhodines (aminophenazines, aminonaphthophenazines), and by means of their diazo derivatives can be de-amidated, yielding in this way azonium salts; consequently they may be considered as amidated azonium salts.
NPFF Neuropeptide FF (FLFQPQRFa) is a mammalian amidated neuropeptide originally isolated from bovine brain and characterized as a pain-modulating peptide, with anti-opioid activity on morphine-induced analgesia.
In normal G-cells of the antrum there are approximately similar concentrations of amidated gastrins and the C-terminal progastrin fragment; concentrations of progastrin and of Gly-extended gastrins are about 10% those of the cleaved C-terminal fragment.