Multistage carcinogenesis involves the sequential genetic or epigenetic changes to a cells DNA, where each step produces a more advanced tumour.

It is not known why women on hormones were more likely to have advanced tumors.

Cancers are classified at different stages depending on how advanced tumours have progressed.

Selected patients with locally advanced tumors may benefit from combined modality treatments.

Currently multimodality treatment is needed (chemotherapy and radiation therapy) for advanced tumors.

This operation is indicated for a subset of patients with more advanced tumors, who can tolerate a pneumonectomy.

Advanced tumors must subvert this last ditch defense by activating telomerase.

But women with more advanced tumors, limited access to radiation treatment, which might be needed after a lumpectomy, or other complicating factors require mastectomies.

However, in locally advanced tumours, surgery may not routinely provide the best chance of cure and is often not technically feasible to perform.

In some cases, the patients' cancer went into remission, offering hope that the new therapy may someday prove extremely valuable in treating advanced tumors.

In contrast to that, inactivation of c-jun in advanced tumors does not impair tumor progression.

Advanced tumours are treated with surgery (radical hysterectomy and bilateral salpingo-opherectomy), radiation therapy and chemotherapy.

Even so, he said, the black women tended to have larger, more advanced tumors when their cancers was diagnosed, which may reflect a faster rate of tumor growth.

Clinical trials for advanced tumors evaluating the use of chemotherapy preoperatively, before radiation therapy, or as adjuvant therapy after surgery are appropriate.

Low p27Kip1 expression can lead to tumor de-differentiation, increased penetration through the gastric wall, lymph node metastasis and advanced tumor stage.

He specializes in the treatment of all head and neck cancers, including complex advanced tumors, skull base tumors and recurrent cancers.

Surgery, radiation therapy, or a combination of both are poor controls for far advanced tumors with extensive destruction of the mandible and with nodal metastases.

Multistage carcinogenesis involves the sequential genetic or epigenetic changes to a cells DNA, where each step produces a more advanced tumour.

The results showed that mutation carriers had lower mean ages of prostate cancer diagnosis, advanced tumor stage, higher tumor grade, and shorter median survival than noncarriers.

However, there are exceptions: Radiation therapy may be used for some advanced tumors, and hormonal therapy is used for some early stage tumors.

Recently, he was organizing a hospice in Bentivoglio for patients with advanced tumors, and he was setting up an outpatient clinic in Bologna to monitor high-risk patients.

Expression of WISP-1 promotes tumor growth, and high WISP-1 expression correlates with advanced tumors of the breast, colon, and lung.

Brachytherapy can be used with the aim of curing the cancer in cases of small or locally advanced tumours, provided the cancer has not metastasized (spread to other parts of the body).

Women taking HRT generally had larger, more advanced tumors than women who developed breast cancer while taking a placebo treatment.2 (But some of these cancers may respond more favorably to treatment.)

The system also bars transplants for some patients with advanced tumors, but, Dr. Roayaie said, some of these patients "are not so far gone that transplant would not be a good option for them."

Women with a common type of very early breast cancer, called intraductal carcinoma, or ductal carcinoma in-situ, are often treated with full mastectomy even as surgeons are moving to less extensive surgery for more advanced tumors.