Postmenopausal estrogen was long recognized to be associated with the risk of adenomatous hyperplasia, often a precursor of endometrial cancer.

Where patients have recovered from this condition, biopsies commonly show multiacinar regenerative nodules (previously known as adenomatous hyperplasia).

Gusberg SB: Precursors of corpus carcinoma estrogens and adenomatous hyperplasia.

Rather, the precursor of peripheral adenocarcinomas has been termed atypical adenomatous hyperplasia (AAH).

The addition of two preinvasive lesions to squamous dysplasia and carcinoma in situ, namely: Atypical adenomatous hyperplasia.

Adenomas and adenomatous hyperplasia of the thyroid and adrenal glands occurs occasionally in MEN 1 patients.