acetophenone

Acetophenone can be obtained by a variety of methods.

In the late 19th and early 20th centuries, acetophenone was used in medicine.

In the example displayed on the right, the compound acetophenone is viewed from the re face.

Commercially significant resins are produced from treatment of acetophenone with formaldehyde and base.

Studies have shown that acetophenone causes chromosomal damage in hamsters.

It is the ketal formed between algestone and acetophenone.

Alternatively, it can also be prepared by oxidation of acetophenone with selenium dioxide.

The result indicated that the products contain styrene, acetophenone and brominated substances.

Under similar conditions bromination of acetophenone gives benzoic acid.

A synthesis using "classical" methodology was reported by Durden and co-workers, starting from acetophenone.

The key steps involved an aldol type condensation of the dianion from 2,4,6-trimethoxybenzoylacetone and a suitable acetophenone.

Reduction of acetophenone occurs between 75 and 150 times slower than benzaldehyde at 0 °C in each respective solvent.

The initial product is a thioacetamide for example that of acetophenone which can again be hydrolyzed to the amide.

Acetophenone's odor activates an odorant receptor (Olfr151) and has been used to condition mice.

Being prochiral, acetophenone is also a popular test substrate for asymmetric hydrogenation experiments.

Reaction product of acetophenone, formaldehyde, cyclohexylamine, methanol and acetic acid 1129.

These results are best explained in terms of substituent effects on the energetics of the acetophenone moiety.

A crosslinking by-product such as acetophenone is fugitive and over time it exudes out of the polymer.

It is prepared using acetophenone, formaldehyde, and an amine hydrochloride in a Mannich reaction.

It is prepared by bromination of acetophenone:

The α-bromination of acetophenone with bromine.

The Knoevenagel reaction of acetophenone with ethyl cyanoacetate was shown to have a rate enhancement of 2.5 times.

Cumylperoxy radicals react with Co(acac)2 to give mainly α-cumyl alcohol and acetophenone.

The substrate in this reduction is acetophenone and the reagent (in blue) a hydride ion.

A typical reaction involving two ketones is that between acetophenone as the enol and acetone: