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One year later, the first effective test for syphilis, the Wassermann test, was developed.
Cardiolipin from a cow heart is used as an antigen in the Wassermann test for syphilis.
The Wassermann test remains a staple of syphilis detection and prevention in some areas, although it has often been replaced by more modern alternatives.
They even demanded that I take a Wassermann test in order to be sure that I wasn't suffering from syphilis.
The Wassermann test has been refined - the Kahn test, and the Kolmer test - and it is rarely used today.
In its toxic phase, the disease was easily confused with typhus, so Fairley developed a complement fixation test for the disease along the lines of the Wassermann test.
In the 1930s the Hinton test, developed by William Augustus Hinton, and based on flocculation, was shown to have fewer false positive reactions than the Wassermann test.
The Wassermann test or Wassermann reaction (WR) is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement-fixation.
This mechanism became the basis for complement-fixation testing methods that enabled the development of serological tests for syphilis (specifically, the development of the Wassermann test by August von Wassermann).
He was the first to describe his triad of medical signs for congenital syphilis: notched incisor teeth, labyrinthine deafness and interstitial keratitis, which was very useful for providing a firm diagnosis long before the Treponema pallidum or the Wassermann test were discovered.
Fleck's case history of the discovery of the Wassermann test for syphilis, was originally published in German in 1935, and republished in English in 1979 after having been cited by Thomas Kuhn as an important influence on his own conception of the history of science.