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However, hemangiomas and lymphangiomas are not seen in Ollier disease.
Ollier disease can be considered a synonym for enchondromatosis.
Ollier disease (enchondromatosis) - when multiple sites in the body develop the tumors.
In Ollier disease isolated enchondromas are present without the presence of hemangiomas.
The exact cause of Ollier disease is not known, although in some cases it may be inherited as an autosomal dominant genetic trait.
Persons with Ollier disease are prone to breaking bones and normally have swollen, aching limbs.
It is important to make the distinction between these diseases, particularly Ollier disease and Maffucci syndrome.
Ollier disease is not normally diagnosed until toddler years because it is not very visible.
Ollier disease is very rare.
Ollier disease is more common than Maffucci syndrome, and presents with multiple enchondromas often in a unilateral distribution.
A small minority of secondary chondrosarcomas occur in patients with Maffucci syndrome and Ollier disease.
Ollier disease carries a high risk of skeletal, visceral and brain malignancy which occurs in approximately 25% of patients.
Multiple enchondromas may present in 3 disorders: Ollier disease, Maffucci syndrome, and metachondromatosis.
Somatic mosaic mutations of this gene have also been found associated to Ollier disease and Maffucci syndrome.
JGCT has been reported in children with Ollier disease and Maffucci syndrome.
Ollier disease is a rare nonhereditary sporadic disorder where intraosseous benign cartilaginous tumors develop close to growth plate cartilage.
The incidence of secondary chondrosarcoma in Ollier disease is not known, but may be as high as 25%, pelvis and shoulder girdle being the commonest locations.
When the enchondromas of Ollier Disease are accompanied by substantial, most often benign, proliferation of blood vessels (hemangiomas), the array of symptoms is known as Maffucci Syndrome.
Ollier disease primarily affects the long bones and cartilage of the joints of the arms and legs, specifically the area where the shaft and head of a long bone meet (metaphyses).
Multiple Enchondromatosis Multiple Cartilaginous Enchondroses Dyschondroplasia Enchondromatosis None Ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia).
Ollier disease manifests as greater than normal growth of the cartilage in the long bones of the legs and arms so that growth is abnormal and the outer layer (cortical bone) of the bone becomes thin and more fragile.
Ollier disease can be considered a synonym for enchondromatosis.
Ollier disease (enchondromatosis) - when multiple sites in the body develop the tumors.
In 1881 he described a disorder characterized by enchondromatosis associated with multiple cavernous angiomas.
His name is associated with Ollier's disease, a bone disorder that is also known as multiple enchondromatosis.
Maffucci syndrome is enchondromatosis with hemangiomatosis.
Bone dysplasias, including Paget's disease, fibrous dysplasia, enchondromatosis, and hereditary multiple exostoses, increase the risk of osteosarcoma.
Gell JS, Stannard MW, Ramnani DM, et al.: Juvenile granulosa cell tumor in a 13-year-old girl with enchondromatosis (Ollier's disease): a case report.
Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchondromatosis and primary failure of tooth eruption.
Multiple Enchondromatosis Multiple Cartilaginous Enchondroses Dyschondroplasia Enchondromatosis None Ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia).