The supraoptic nucleus is an important "model system" in neuroscience.

Similar magnocellular neurons are found in the supraoptic nucleus.

The supraoptic nucleus as a "model system"

This research took place mostly in cells from the hypothalamic supraoptic nucleus, or SON.

Vasopressin is released into the brain in a circadian rhythm by neurons of the supraoptic nucleus.

However many of the direct inputs to the supraoptic nucleus come from neurons just outside the nucleus (the "perinuclear zone").

Anatomical studies using electron microscopy have shown that the morphology of the supraoptic nucleus is remarkably adaptable.

These neurons project to the supraoptic nucleus and paraventricular nucleus to regulate the activity of vasopressin-secreting neurons.

Magnocellular neurosecretory cells are large neuroendocrine cells within the supraoptic nucleus and paraventricular nucleus of the hypothalamus.

For example, dynorphin that is made in magnocellular vasopressin neurons of the supraoptic nucleus is important in the patterning of electrical activity.

Fibers from supraoptic nuclei are concerned with ADH secretion; paraventricular nuclei with oxytocin.

The supraoptic nucleus (SON) is a nucleus of magnocellular neurosecretory cells in the hypothalamus of the mammalian brain.

Suckling by the baby stimulates the paraventricular nuclei and supraoptic nucleus in the hypothalamus, which signals to the posterior pituitary gland to produce oxytocin.

Neurophysins are carrier proteins which transport the hormones oxytocin and vasopressin to the posterior pituitary from the paraventricular and supraoptic nucleus of the hypothalamus.

Secretin is found in the magnocellular neurons of the paraventricular and supraoptic nuclei of the hypothalamus and along the neurohypophysial tract to neurohypophysis.

Oxytocin in the supraoptic nucleus co-exists with enkephalin, dynorphin, cocaine-and amphetamine regulated transcript (CART) and cholecystokinin.

Modulation of synaptic transmission: In the supraoptic nucleus of the hypothalamus, rapid changes in astrocyte morphology have been shown to affect heterosynaptic transmission between neurons.

Most of the circulating oxytocin and vasopressin hormones are synthesized in magnocellular neurosecretory cells of the supraoptic nucleus and paraventricular nucleus of the hypothalamus.

Hypothalamic efferents in DLF arise from the paraventricular nucleus, supraoptic nucleus and periventricular nucleus, and send information to multiple areas, including:

These areas project to the supraoptic nucleus and paraventricular nucleus, which contain neurons that secrete the antidiuretic hormone, vasopressin, from their nerve endings in the posterior pituitary.

Neurons in the OVLT and SFO project to the supraoptic nucleus and paraventricular nucleus, and also to preoptic hypothalamic areas.

Vasopressin is produced by magnocellular neurosecretory neurons in the Paraventricular nucleus of hypothalamus (PVN) and Supraoptic nucleus (SON).

Studies in female mice have shown that both supraoptic nucleus (SON) and paraventricular nucleus (PVN) lose approximately one-third of IGF-1R immunoreactive cells with normal aging.

Specific parts of the brain such as the supraoptic nucleus produce oxytocin which acts on cells in locations such as the ventral pallidum to produce the behavioral effects of oxytocin.

Of the afferent inputs to the supraoptic nucleus, most contain either the inhibitory neurotransmitter GABA or the excitatory neurotransmitter glutamate, but these transmitters often co-exist with various peptides.