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The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha).
Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines.
Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1a, an inhibitor of primitive normal hematopoietic cells.
CCR5 is known to have an affinity for macrophage inflammatory protein (MIP) and is thought to play a role in inflammatory immunological responses.
They induce the production by PMN of the chemokines MIP-1α and MIP-1β (macrophage inflammatory protein) to recruit macrophages.
PT has been found to inhibit the early transcription of keratinocyte-derived chemokine, macrophage inflammatory protein 2 and LPS-induced CXC chemokine.
For example, Dr. Oliver Smithies, Dr. Donald Cook, and Dr. Melinda Beck at the University of North Carolina School of Medicine recently investigated the role of MIP-1alpha - MIP stands for macrophage inflammatory protein - in lung infections.