Coltivirus have dsRNA genome with a double-capside structure and icosahedral symmetry.

While members of Orbivirus are known to cause diseases in animals, members of Coltivirus are associated with human diseases.

"ViralZone: Coltivirus."

There are four genera in this viral family (Orthoreovirus, Rotavirus, Orbivirus, and Coltivirus) and all four are known to include species that infect humans.