Morning Glory Syndrome is extremely rare.

Morning glory syndrome may be associated with Aicardi syndrome, a condition found exclusively in girls (lethal in males).

Mario Bonds, a contestant on Season 2 of the Glee Project was diagnosed with Morning Glory Syndrome at age 9.

Coloboma of optic nerve, also called Morning Glory syndrome, is a rare defect of the optic nerve that causes moderate to severe blindness.

Morning Glory syndrome is a congenital anomaly of the optic disc in which there is a funnel-shaped excavation of the posterior fundus incorporating the optic nerve, surrounded by an elevated annulus of chorioretinal pigment.

Morning Glory Syndrome typically affects only one eye; but cases has been documented of bilateral Morning Glory Syndrome (those with that stage of severe blindness have other disorders as well, like autism).