Endogenous or unipolar depression has a biochemical basis, often occurring without apparent reason.

The disorders associated with most disability in high income countries were unipolar major depression (20%) and alcohol use disorder (11%).

Many cases of bipolar depression are very similar to those of unipolar depression.

Therefore, the patient can be misdiagnosed with unipolar depression and be given antidepressants.

After a moment of silence, Kennett said, "A unipolar depression.

Lithium appears effective at lowering the risk in those with bipolar disorder and unipolar depression to nearly the same levels as the general population.

There was no association for those with unipolar depression or their relatives.

Women are more likely than men to show unipolar depression.

Women are more likely to suffer from unipolar depression, anxiety, eating disorders, and post-traumatic stress disorder.

A 2008 analysis of a large study of patients with unipolar major depression found a rate of 23.5% for melancholic features.