The opponens pollicis receives its blood supply from the Superficial palmar arch.

This is in contrast to the superficial palmar arch, which is formed predominantly by the ulnar artery.

The superficial palmar arch is more distally located than the deep palmar arch.

They also anastomose with common palmar digital arteries (from the superficial palmar arch), also via perforating arteries.

It arises from the brachial artery and terminates in the superficial palmar arch, which joins with the superficial branch of the radial artery.

The superficial palmar arch is accompanied by a pair of venae comitantes which constitute the superficial palmar venous arch.

Three common palmar digital arteries arise from the convexity of the superficial palmar arch and proceed distally on the second, third, and fourth lumbricales muscles.

Running forward, it passes through, occasionally over, the thenar muscles, which it supplies, and sometimes anastomoses with the terminal portion of the ulnar artery, completing the superficial palmar arch.

If one were to fully extend the thumb and draw a line from the distal border of the thumb across the palm, this would be the level of the superficial palmar arch.

At the lower border of the transverse head of the adductor pollicis, this vessel anastomoses with the princeps pollicis, and gives a communicating branch to the superficial palmar arch.

There are four separate sources of blood supply for these muscles: the superficial palmar arch, the common palmar digital artery, the deep palmar arch, and the dorsal digital artery.