In: The retinal pigment epithelium: function and disease.

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium.

This enzyme from retinal pigment epithelium, catalyses the reduction of 11-cis-retinol to 11-cis-retinal.

In the mammalian retina, they are believed to be confined to the retinal pigment epithelium.

The retinal pigment epithelium maintains the outer blood-retinal barrier.

The build-up of fluid seems to occur because of small breaks in the retinal pigment epithelium.

Also, vision can be impaired if the streaks progress to the fovea and damage the retinal pigment epithelium.

Expression was found in iris, ciliary body, and retinal pigment epithelium at E14.5 and became more intense after birth.

It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.

In the early stages of Choroideremia, the choroid and the retinal pigment epithelium initially deteriorate.

There is diffuse depigmentation of the retinal pigment epithelium with the greatest effect occurring at the macula.

Retinal pigment epithelium.

The optic cup then delaminates into two layers: The neural retina and the retinal pigment epithelium.

This mutation results in defective retinal pigment epithelium phagocytosis of photoreceptor outer segments.

These melanocytes are distinct from the retinal pigment epithelium cells underlying the retina that do not form melanomas.

Beneath the photoreceptors is a layer of dark tissue known as the retinal pigment epithelium, or RPE.

This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina.

The outer layer is highly pigmented, continuous with the retinal pigment epithelium, and constitutes the cells of the dilator muscle.

As A2E buildup from the photoreceptor cells collects in the retinal pigment epithelium, severe visual loss occurs.

Both during development and in adult life, the retinal pigment epithelium is critical to retinal function [ 63 ] .

This is part of the bleach and recycle process of retinoids in the photoreceptors and retinal pigment epithelium.

The white dots are small and located in the posterior pole at the level of the retinal pigment epithelium (RPE).

The retinal pigment epithelium transports metabolic waste from the photoreceptors across Bruch's membrane to the choroid.

Additionally, there were small areas where photoreceptor nuclei extended externally and were in direct contact with the retinal pigment epithelium (Figure 4N).

The blood retinal barrier has two components: the retinal vascular endothelium and the retinal pigment epithelium.