Prostatic intraepithelial neoplasia - prostate-cancer.org.

High-grade prostatic intraepithelial neoplasia is equivalent to CIS of the prostate.

It may be referred to simply as prostatic intraepithelial neoplasia (abbreviated as PIN).

Morphometric analysis and clinical followup of isolated prostatic intraepithelial neoplasia in needle biopsy of the prostate.

Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.

Prostatic intraepithelial neoplasia, grade III (C61.9)

Chromosome analysis has also shown loss of the short arm of chromosome 8 (8p12-22) in prostatic intraepithelial neoplasia, primary tumours and metastatic cancer.

The study of 23 men ages 40-75, diagnosed with high-grade prostatic intraepithelial neoplasia at biopsy -- lesions that indicate an increased risk of developing prostate cancer.

Eligibility: Documented high grade prostatic intraepithelial neoplasia (HGPIN) confirmed by the central reference pathologist.

Initially, small clumps of cancer cells remain confined to otherwise normal prostate glands, a condition known as carcinoma in situ or prostatic intraepithelial neoplasia (PIN).

Over Expression of the cell cycle inhibitor p16INK4A in high grade prostatic intraepithelial neoplasia predicts early relapse in prostate cancer patients.

Berg said the BP1 gene also appeared overactive in prostatic intraepithelial neoplasia, or PIN, a pre-cancerous change in prostate tissue.

LOH has been reported to be observed in 12-89% of high-grade prostatic intraepithelial neoplasia (PIN) and 35-86% of prostatic adenocarcinomas.

In the trial, toremifene is being given to men suffering from high grade prostatic intraepithelial neoplasia, a condition that could be a precursor to prostate cancer, as a 20 mg dose.

ACK1 transgenic mice, expressing activated ACK1 specifically in prostate gland has been reported; these mice develop prostatic intraepithelial neoplasia (PINs).

On a subsequent biopsy, given the diagnosis of ASAP, the chance of finding prostate adenocarcinoma is approximately 40%; this is higher than if there is high-grade prostatic intraepithelial neoplasia (HGPIN).

In urologic pathology, high-grade prostatic intraepithelial neoplasia, abbreviated HGPIN, is an abnormality of prostatic glands and believed to precede the development of prostate adenocarcinoma (the most common form of prostate cancer).

While greater than 85% of terminally differentiated secretory cells in normal human prostate display strong nuclear staining for p27, all cases of high-grade prostatic intraepithelial neoplasia, invasive carcinoma, and pelvic lymph node metastases studied by DeMarzo et al. showed down-regulation of p27 [ 1 ] .

Also called prostatic intraepithelial neoplasia.

Having high-grade prostatic intraepithelial neoplasia may increase the risk of developing prostate cancer.

After 24 weeks, the mice given plain water had developed prostate cancer while the mice given water with green tea catechins showed only prostatic intraepithelial neoplasia (PIN) lesions.

A study assigned 60 men with high-grade prostatic intraepithelial neoplasia (HGPIN) to take green tea catechin capsules (600 mg / day) or a placebo.

Men with high-grade prostatic intraepithelial neoplasia (HGPIN) who took lycopene supplements for 2 years had a greater decrease in PSA levels and fewer cases of prostate cancer than those who did not.

In an earlier study, men with high-grade prostatic intraepithelial neoplasia (HGPIN) were given either a selenium supplement (200 ug/ day) or a placebo for 3 years or until they were diagnosed with prostate cancer.

A report of one patient with high-grade prostatic intraepithelial neoplasia (HGPIN) who received Zyflamend 3 times/ day for 18 months showed that PSA levels were not affected.