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Microscopic haematuria with or without proteinuria may be seen.
Microscopic haematuria and hypertension may also been seen.
Many physicians also believe that simple renal cysts commonly cause microscopic haematuria and mild proteinuria.
Inhalation or skin contact with 4-COT produces acute toxic effects, initially appearing as macroscopic or microscopic haematuria.
For example, should further diagnostic procedures (such as renal biopsy) be performed, after simple renal cysts are found in a patient with mild proteinuria or microscopic haematuria?
Sultana SR, Goodman CM, Byrne DJ, et al.: Microscopic haematuria: urological investigation using a standard protocol.
In the only documented case in which rechallenge has been undertaken, low dose rechallenge with both mesalazine and sulphasalazine caused microscopic haematuria suggesting dose independent hypersensitivity to 5-ASA.
Interestingly, neither the prevalence of past symptoms nor that of proteinuria and microscopic haematuria differed in patients with and without simple renal cysts, and the red blood cell count was also the same in both groups.