Manship's work is often considered to be a major precursor to Art Deco.
Population based studies show that atherosclerosis the major precursor of cardiovascular disease begins in childhood.
The system is a major precursor of the more generic "lean manufacturing."
This failure is hypothesized to be the major precursor for all psychotic states.
Ethylene has long represented the major nonfermentative precursor to ethanol.
Organic surrealism was one of the major precursors to abstract expressionism.
Progesterone is also a major precursor for other hormones, like the estrogens and testosterone.
It is also generally considered a major precursor to the Italian neorealist movement.
His work seems to have been a major precursor of the op art movement, although he is not generally identified as a member of it.
The Impact is a major precursor of what appears to be an impending new era in cars: a radical change from gasoline to electricity.