The company they work for is a major hindrance in this endless struggle.

Ticket prices are regularly cited as a major hindrance to developing new audiences, particularly young people.

This is obviously a major hindrance for the card counter.

A major hindrance to Italy's decision on what to do about the war was the political instability throughout Italy in 1914.

Political instability in Pakistan has been a major hindrance.

A major hindrance to its acceptance seems to be that it is very slow in bearing, said to take 12 years or more from seed.

Malaria is commonly associated with poverty and may also be a major hindrance to economic development.

Religion, he concluded, was a major hindrance to becoming modern.

The high seed content of this variety is a major hindrance in out-of-hand eating.

The pass was once known to be a major hindrance to land transportation with its winding and steep grade.