Furthermore, lobeline can be modified to lobelane which decreased methamphetamine self-administration in rats.

Lobeline binds at this site.

It contains lobeline.

Since lobeline can be toxic in excessive quantities, it's probably safer to enjoy the flower as a visual stimulant in the garden.

Lobelia chinensis contains lobeline, lobelanine, isolobelanine, lobelanidine, and various flavonoids.

He has also studied the use of lobeline as a nicotine blocker, and various psychoactive substances including anti-depressants and anti-anxiety agents.

All lobelias produce lobeline to some extent, and extracts from various species are still used in naturopathic and homeopathic remedies for a variety of ailments.

Extracts of Lobelia inflata contain lobeline, which showed positive effects in the treatment of multidrug-resistant tumor cells in vitro.

The agency said several manufacturers of nonprescription smoking deterrents had discussed conducting possible clinical trials on lobeline sulfate and silver acetate, two ingredients found in several products.

Ketanserin (KET) and the drug Lobeline also bind to the TBZ binding site conformation.

The agency's action "will not have a major effect on the company," she said, adding that it does not advertise or promote Bantron, which lists lobeline sulfate as its main ingredient.

The effects of nicotine and lobeline are quite similar, with psychoactive effects at small dosages and with unpleasant effects including vomiting, muscle paralysis, and trembling at higher dosages.

Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of the Tree Tobacco (Nicotiana glauca), lobeline of the indian tobacco, and the toxic alkaloid coniine from poison hemlock, which was used to put Socrates to death.