While rare, dural sinus thrombosis may lead to hemorrhagic infarction with serious consequences including epilepsy, neurological deficits, or death.

It has been suggested that infarction alone causes milder symptoms than either hemorrhage or hemorrhagic infarction (infarction followed by hemorrhage into the damaged tissue).

Many pituitary tumors (25%) are found to have areas of hemorrhagic infarction on MRI scans, but apoplexy is not said to exist unless it is accompanied by symptoms.

Hemorrhagic infarction (bleeding) of the spinal cord can occur as a sequel to acute injury, such as that caused by intervertebral disc extrusion (being forced or pressed out).