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Effect of Galega officinalis L. extract on platelet aggregation in rats.
Galega officinalis (French lilac) was used for diabetes treatment in traditional medicine for centuries.
Galega officinalis has been known since the Middle Ages for relieving the symptoms of diabetes mellitus.
The species Galega officinalis and Galega orientalis are familiar in cultivation.
Inhibitory effects of Galega officinalis on glucose transport across monolayers of human intestinal epithelial cells (Caco-2).
Be careful not to confuse goat's rue (Galega officinalis) with rue (Ruta graveolens).
Galega officinalis, commonly known as goat's rue, French lilac, Italian fitch or professor-weed, is an herbaceous plant in the Faboideae subfamily.
Georges Tanret identified an alkaloid (galegine) from Galega officinalis that was evaluated in clinical trials in patients with diabetes in the 1920s and 1930s.
The folk remedy French lilac (Galega officinalis), was used to treat the symptoms of diabetes, and towards the end of the nineteenth century it was discovered to contain guanidine.
While working at the Chemistry Institute of the University of Vienna, Slotta synthesized compounds, analogous to plant extract from French lilac (Galega officinalis), then used to treat symptoms of diabetes.
The biguanide class of antidiabetic drugs, which also includes the withdrawn agents phenformin and buformin, originates from the French lilac or goat's rue (Galega officinalis), a plant used in folk medicine for several centuries.
Examples include Galega officinalis which contains galegine and guanidine, upon which the anti-diabetic drug metformin is modelled and Artemisia annua which is the source of the anti-malarial drug artemisinin.
French Honeysuckle, French Lilac, Galega, Galéga, Galega officinalis, Galega bicolor, Galega patula, Galegae Officinalis Herba, Geissrautenkraut, Goat's Rue Herb, Italian Fitch.
While training at the Hôpital de la Pitié, French diabetologist Jean Sterne studied the antihyperglycemic properties of galegine, an alkaloid isolated from Galega officinalis, which is related in structure to metformin and had seen brief use as an antidiabetic before the synthalins were developed.