The foramen rotundum, an opening in the bone of the orbit, is present.

The average diameter of the foramen rotundum in adults is 3.55 mm.

The foramen rotundum evolves in shape throughout the fetal period, and from birth to adolescence.

One makes its appearance in each wing between the foramen rotundum and foramen ovale about the eighth week.

The foramen rotundum is a circular aperture at its anterior and medial part; it transmits the maxillary nerve.

Behind the medial end of the superior orbital fissure is the foramen rotundum, for the passage of the maxillary nerve.

The maxillary nerve passes through and exits the skull via the pterygopalatine fossa and the foramen rotundum.

The foramen rotundum contains the maxillary branch of trigeminal cranial nerve (CN V).

The foramen ovale is situated in the posterior part of the sphenoid bone, posterolateral to the foramen rotundum.

The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa.

The maxillary nerve, division V of the trigeminal nerve travels through the lower portion of the sinus and exits via the foramen rotundum.

The ophthalmic, maxillary and mandibular branches leave the skull through three separate foramina: the superior orbital fissure, the foramen rotundum and the foramen ovale.

Behind and lateral to the foramen rotundum is the foramen ovale, which transmits the mandibular nerve, the accessory meningeal artery, and the lesser superficial petrosal nerve.

Below the medial end of the superior orbital fissure is a grooved surface, which forms the posterior wall of the pterygopalatine fossa, and is pierced by the foramen rotundum.

The foramen rotundum is one of the several circular apertures (the foramina) located in the base of the skull, in the anterior and medial part of the sphenoid bone.

It begins at the middle of the trigeminal ganglion as a flattened plexiform band, and, passing horizontally forward, it leaves the skull through the foramen rotundum, where it becomes more cylindrical in form, and firmer in texture.

The middle meningeal nerve (meningeal or dural branch) is given off from the maxillary nerve (CN V) directly after its origin from the semilunar ganglion, before CN V enters the foramen rotundum.

The earliest perfect ring-shaped formation of the foramen spinosum was observed in the 8th month after birth and the latest in 7 years after birth in a developmental study on the foramen rotundum, foramen ovale and foramen spinosum.

In 1856 he cut down and removed the entire trunk of the second branch of the fifth pair of cranial nerves, the nerve being cut from the infra-orbital foramen to the foramen rotundum, at the base of the skull, involving an operation through the malar bone.