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Theoretically the use of emetine in children is not advised.
Both recovered with the treatment for heart failure and withdrawal of emetine.
When present, they are more transient than with emetine.
Patients receiving emetine should be monitored for changes in pulse, blood pressure and electrocardiography.
The active ingredient is a powdered white alkaloid called emetine."
In practice, emetine still produces a more dramatic clinical response thanchloroquine or metronidazole.
In vitro testing showed emetine was more effective than Metronidazole or furazolidone.
Till today, emetine remains one of the best drugs for treating amoebic liver abscess.
And right now they're jolting his gums and the pus-sacs with emetine.
One patient who was given fifteen injections of emetine in a dose of 60 mgm.
Chemically, it is closely related to emetine.
The identification of emetine as a more potent agent improved the treatment of amoebiasis.
Cephaeline is a desmethyl analog of emetine also found in ipecac root.
Emetine should always be given deep intramuscularly or deep subcutaneously but never intravenously.
An early account described infection of British troops in Egypt in 1916 who recovered following treatment with emetine.
Additionally, emetine could be administered hypodermically which still produced nausea, but not to the degree experienced in oral administration.
While use of emetine still caused nausea, it was more effective than the crude extract of ipecac root.
See biosynthesis of Emetine.
He employed ipecacuanha (emetine) empirically without knowing that it had a specific action on the amoeba histolytica.
The actions of ipecac are mainly those of its major alkaloids, emetine (methylcephaeline) and cephaeline.
Systemic amoebicidal drugs include emetine, dehydroemetine, chloroquine diphosphate, metronidazole, and tinidazole.
In patients having myocardial disease or marked hypertension, emetine can be used for amoebic liver abscess, as the benefits from it may outweigh possible hazards.
Early use of emetine was in the form of oral administration of the extract of ipecac root, or ipecacuanha.
Heavy or overusage of emetine can carry the risk of developing proximal myopathy and/or cardiomyopathy.
Overdosage of emetine produces focal necrosis of cardiac muscle resulting in cardiac failure and sudden death.