A corpus luteum cyst rarely occurs at age 50+, because eggs are no longer being produced in menopausal women.

Although ovarian cancer is cystic, it does not arise from benign corpus luteum cysts.

Most common causes for adnexal masses in premenopausal women are follicular cysts and corpus luteum cysts.

Pain, which occurs primarily mid-cycle or after a minor delay in menstruation (at the time of the rupture of a corpus luteum cyst, for example).

A corpus luteum cyst will cause BBTs to stay elevated and prevent menstruation from occurring until it resolves, which could take weeks or months.

Pelvic ultrasound reveals in the affected ovary a large corpus luteum cyst with signs of hemorrhage in it and/or free fluid (blood) in the stomach.

A Corpus luteum cyst is a type of ovarian cyst which may rupture about the time of menstruation, and take up to three months to disappear entirely.

The fertility drug clomiphene citrate (Clomid, Serophene), used to induce ovulation, increases the risk of a corpus luteum cyst developing after ovulation.

Both techniques have lower specificity in premenopausal women than in postmenopausal women, due to the cyclic menstrual changes in premenopausal ovaries (e.g., transient corpus luteum cysts) that can cause difficulty in interpretation.