This subset of complexes are often discussed within the subfield of bioorganometallic chemistry.

Bioorganometallic chemistry is the study of biologically active molecules that contain carbon directly bonded to metals or metalloids.

Within the realm of bioorganometallic chemistry is the study of the fates of synthetic organometallic compounds.

In the area of bioorganometallic chemistry, organoiron species are found at the active sites of the three hydrogenase enzymes as well as carbon monoxide dehydrogenase.

Carbon monoxide is a nutrient for methanogenic bacteria, a building-block for acetylcoenzyme A. This is the theme for the emerging field of bioorganometallic chemistry.

The journal includes reviews, full papers, communications, working methods papers, crystallographic reports, and occasional reports on relevant conferences of applied work in the field of organometallics, including bioorganometallic chemistry, and metal/organic ligand coordination chemistry.