Its two biggest-selling drugs treat hypertension and ulcers.

Premarin, an estrogen product made from the urine of pregnant horses, is already the biggest-selling drug in the United States.

Celebrex had $3.3 billion in sales last year, making it one of the biggest-selling drugs in the world.

Until recently, the biggest-selling drug in Japan was an anti-cancer medication that, it now seems, may have had no effect at all.

And the biggest blow could come in 2010 or 2011 when the anticholesterol pill Lipitor, the world's biggest-selling drug, begins losing patent protection.

Pravachol had $2.8 billion in sales last year, making it the company's biggest-selling drug.

For instance, he said in an interview that Neotrofin might work for every neurological disease, potentially becoming the biggest-selling drug ever.

Cipro has been Bayer's biggest-selling drug for several years.

But in the next two years, some of its biggest-selling drugs will lose patent protection and be opened to generic competition.

Antidepressants are among the biggest-selling drugs in the world and have long been viewed by doctors as relatively safe.