A clinician should immediately consider acrodynia in an afebrile child who is sweating profusely.

Infantile acrodynia (childhood mercury poisoning) is characterized by excessive perspiration.

Dr. Warkany found that in a single decade in England, acrodynia had killed 585 children.

The prevalence of acrodynia decreased greatly after calomel was excluded from most teething powders in 1954.

Only one previous case of acrodynia associated with latex paint use has been reported during the last 30 years, C.D.C. researchers said.

In another major contribution, Dr. Warkany discovered the cause of acrodynia, or pink disease, enabling its eradication.

The symptoms of acrodynia, which affects children, includes reddened limbs, hair and teeth loss, hypertension, weight loss, and even death.

It was removed from most powders in 1954 when it was shown to cause "pink disease" (acrodynia), a form of mercury poisoning.

Mercury poisoning can result in several diseases, including acrodynia (pink disease), Hunter-Russell syndrome, and Minamata disease.

They found a striking parallel in acrodynia, a 1930's ailment that occurred in some children exposed to mercury in lotions and teething powders.

In 1934 a Hungarian physician Paul György discovered a substance that was able to cure a skin disease in rats (dermititis acrodynia).

Infantile acrodynia induced by chronic low-dose mercury exposure, leading to elevated catecholamine accumulation and resulting in a clinical picture resembling pheochromocytoma.

This case of acrodynia was traced to exposure of mercury from a carton of 8-foot fluorescent light bulbs that had broken in a potting shed adjacent to the main nursery.

Cachexia is seen in patients with cancer, AIDS, chronic obstructive lung disease, multiple sclerosis, congestive heart failure, tuberculosis, familial amyloid polyneuropathy, mercury poisoning (acrodynia) and hormonal deficiency.

Attention was focused on the paint hazard last August when a four-year-old Michigan boy was hospitalized with acrodynia, a rare type of childhood mercury poisoning characterized by leg cramps, skin peeling and nerve problems.

At a succession of hearings, the so-called Mercury Moms presented their research on acrodynia and thimerosal, and a neurologist described his research showing that tiny amounts of thimerosal triggered brain-cell death.

Infantile acrodynia (also known as "calomel disease", "erythredemic polyneuropathy", and "pink disease") is a type of mercury poisoning in children characterized by pain and pink discoloration of the hands and feet.

At first, the cause of the acrodynia epidemic among infants and young children was unknown; however, mercury poisoning, primarily from calomel in teething powders, began to be widely accepted as its cause in the 1950s and 60s.

Warkany and Hubbard (1953) noted in their seminal paper establishing mercury as the cause of infantile acrodynia that "... in modern times the capricious behavior of mercurial diuretics has been rather disturbing to those who use them frequently.

After finding associations between mercurial diuretics and "mercurial" nephrotic syndrome, in addition to the sharp decline in infantile acrodynia cases after the late 1950s following the removal of many sources of childhood mercury exposure, the dangers of mercurial diuretics were realized.