The exact cause of Rosai-Dorfman disease is unknown.

The symptoms and physical findings associated with Rosai-Dorfman disease vary depending upon the specific areas of the body that are affected.

Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a rare disorder of unknown etiology that is characterized by abundant histiocytes in the lymph nodes throughout the body.

He is the principal author and editor of a major textbook in that field, and he has characterized novel medical conditions such as Rosai-Dorfman disease and the desmoplastic small round cell tumor.

Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a rare disorder of unknown etiology that is characterized by abundant histiocytes in the lymph nodes throughout the body.