Information from the face and mouth is represented in the spinal trigeminal nucleus.

The spinal trigeminal nucleus represents pain/temperature sensation from the face.

Within the spinal trigeminal nucleus, information is represented in an onion skin fashion.

The spinal trigeminal nucleus contains a pain/temperature sensory map of the face and mouth.

The spinal trigeminal nucleus sends pain/temperature information to the thalamus.

Thus the spinal trigeminal nucleus receives input from cranial nerves 5,7,9,10.

Exactly how pain/temperature fibers from the face are distributed to the spinal trigeminal nucleus has been a subject of considerable controversy.

The spinal trigeminal nucleus receives pain/temperature fibers.

Spinal trigeminal nucleus (V) - sensory (crude touch, temperature and pain)

The spinal trigeminal nucleus is further subdivided into three parts, from rostral to caudal:

It lies laterally to the gracile nucleus and medial to the spinal trigeminal nucleus in the medulla.

The spinal trigeminal nucleus is a nucleus in the medulla that receives information about deep/crude touch, pain, and temperature from the ipsilateral face.

Damage to the spinal trigeminal nucleus causes absence of pain on the ipsilateral side of the face, as well as an absent corneal reflex.

It is found at the base of the skull and projects to trigeminal brain stem areas including principalis, spinal trigeminal nucleus, interpolaris, and caudalis.

From the spinal trigeminal nucleus, secondary fibers cross the midline and ascend in the trigeminothalamic (quintothalamic) tract to the contralateral thalamus.

These fibers transmit information to secondary afferent cell bodies in the oralis and interpolaris portions of the spinal trigeminal nucleus plus the principal nucleus.

The neural regions involved in the sneeze reflex is located in the brainstem along the ventromedial part of the spinal trigeminal nucleus and the adjacent pontine-medullary lateral reticular formation.

Its axons take an unusual course, traveling dorsally and looping around the abducens nucleus, then traveling ventrally to exit the ventral pons medial to the spinal trigeminal nucleus.

From caudal to rostral (i.e., going up from the medulla to the midbrain) they are the spinal trigeminal nucleus, the main trigeminal nucleus, and the mesencephalic trigeminal nucleus.

The intermediate and deep layers also receive input from the spinal trigeminal nucleus, which conveys somatosensory information from the face, as well as the hypothalamus, zona incerta, thalamus, and inferior colliculus.

This bundle of incoming fibers can be identified in cross sections of the pons and medulla as the spinal tract of the trigeminal nucleus, which parallels the spinal trigeminal nucleus itself.

Finally, SP-immunoreactive cell bodies have been found in the human brainstem; for example, in the superior colliculus and in the spinal trigeminal nucleus [ 22 32 ] , in which we did not find NK-ir perikarya.

Pain/temperature fibers from peripheral nociceptors are carried in cranial nerves V, VII, IX, and X. On entering the brainstem, sensory fibers are grouped together and sent to the spinal trigeminal nucleus.

In the cerebellum, the PICA supplies blood to the posterior inferior portion of the cerebellum, the inferior cerebellar peduncle, the nucleus ambiguus, the vagus motor nucleus, the spinal trigeminal nucleus, the solitary nucleus, and the vestibulocochlear nuclei.

The expression of CCL2 in neurons is mainly found in the cerebral cortex, globus pallidus, hippocampus, paraventricular and supraoptic hypothalamic nuclei, lateral hypothalamus, substantia nigra, facial nuclei, motor and spinal trigeminal nuclei, gigantocellular reticular nucleus and in Purkinje cells in the cerebellum.