When such a polarized cell divides, the two daughter cells receive different chemical allocations.

Recently, T17 polarized cells have been shown to mediate the regression of established tumors in mice.

Upon loss of Orb6 kinase function, cells fail to maintain a polarized cell shape and become round.

This influx of sodium depolarizes the formerly polarized cell membrane.

More pathways exist in specialized cells, such as melanocytes and polarized cells.

This is particularly evident in epithelial and endothelial cells, but also describes other polarized cells, such as neurons.

We therefore compared the responses of polarized cells to encounters with wild-type bacteria at either the apical or basolateral membranes.

Epithelial cells are one example of a polarized cell type, featuring distinct 'apical', 'lateral' and 'basal' plasma membrane domains.

The apical membrane of a polarized cell is the surface of the plasma membrane that faces inward to the lumen.

The basolateral membrane of a polarized cell is the surface of the plasma membrane that forms its basal and lateral surfaces.

Although anterior-posterior patterning mutants fail to full extend their germ-bands, during the fast phase the elongation length is normal despite defects in polarized cell intercalation.

One mechanism by which Myosin II might promote polarized cell remodeling is through contractile activity that creates tension orienting junctional disassembly.

JIPs on the other hand, are apparently transport proteins, responsible for enrichment of MAPK signaling components in certain compartments of polarized cells.

The exact function of the anchor protein has been the subject of much speculation, but it appears to act as an intracellular signal that targets proteins to the apical surface in polarized cells.

Classical examples of polarized cells are described below, including epithelial cells with apical-basal polarity, neurons in which signals propagate in one direction from dendrites to axons, and migrating cells.

A mesenchymal-epithelial transition (MET) is a reversible biological process that involves the transition from motile, multipolar or spindle-shaped mesenchymal cells to planar arrays of polarized cells called epithelia.

This model is consistent with the recent report that MHCK-A displays enrichment into anterior F-actin-rich protrusions of polarized cells during chemotaxis, and into phagocytic and macropinocytotic extensions [ 23 ] .

We found, however, that the polarized cells secreted Gro-1 in response to exposure to wild-type bacteria at either the apical or basolateral surface, with most of the Gro-1 secreted from the basolateral membrane (Figure 9b).