The dorsal portion of the reticular nucleus has been shown to innervate the mesencephalic trigeminal nucleus and its surrounding area.

First description of electrical coupling in the mammalian CNS ( mesencephalic trigeminal nucleus)

The mesencephalic trigeminal nucleus is not really a "nucleus"; rather, it is a sensory ganglion (like the trigeminal ganglion) that happens to be embedded in the brainstem.

From caudal to rostral (i.e., going up from the medulla to the midbrain) they are the spinal trigeminal nucleus, the main trigeminal nucleus, and the mesencephalic trigeminal nucleus.

In the adult rat central nervous system (CNS), plexin A4 was present in neurons and fibers throughout the brain and spinal cord, including neocortex, hippocampus, lateral hypothalamus, red nucleus, facial nucleus, and the mesencephalic trigeminal nucleus.