Intracardiac injection has appeared several times in the media, although artistic liberties surrounding the procedure are common.

At the end of the experiment the rats were killed by intracardiac injection of sodium pentobarbitone and exsanguination.

Intracardiac injections are injections that are given directly into the heart muscles or ventricles.

Additionally, KCl is used (albeit rarely) in fetal intracardiac injections in second- and third-trimester induced abortions.

There is a small, fresh puncture wound through the anterior left ventricle, which I assume is the result of Dr. Shelton's commendably accurate intracardiac injection."

Intracardiac injections of drugs are generally used only to provide emergency drugs to a patient if other approaches would be ineffective; for example if drugs cannot be administered intravenously due to individual circumstances.