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Dissolution testing is widely used in the pharmaceutical industry for optimization of formulation and quality control.
Thus, the dissolution testing which is conducted in dissolution apparatus must be able to provide accurate and reproducible results.
It is widely applied in pharmaceutical indusctry to conduct dissolution testing for oral solid dosage forms, mainly tablets.
The performances of dissolution apparatuses are highly dependent on hydrodynamics due to the nature of dissolution testing.
The pharmaceutical industry uses prednisone tablets for the calibration of dissolution testing equipment according to the United States Pharmacopeia (USP).
Research & Development (Formulation) Laboratory: a multi-purpose laboratory for advanced pharmaceutical research including drug formulation development, controlled drug delivery dissolution testing, pre-formulation and micromeritis.
In vitro drug dissolution data generated from dissolution testing experiments can be related to in vivo pharmacokinetic data by means of in vitro-in vivo correlations (IVIVC).
Analytical data from drug dissolution testing are sufficient in many cases to establish safety and efficacy of a drug product without in vivo tests, following minor formulation and manufacturing changes (Qureshi and Shabnam, 2001).
In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles.
