PMMA microspheres have been used for cosmetic soft tissue augmentation outside of the USA in an estimated 200,000 procedures over the past 10 years.

Another strategy developed by NFB in the area of soft tissue augmentation with the use of cholecyst-derived extracellular matrix (CEM).

Surgically, it is known for its position against using animal or human cadaver products in bone or soft tissue augmentation due to their potential for contamination of the surgical site.

Klein, A.W. Substances for soft tissue augmentation; In Freedberg I M.D., ed.; Fitzpatrick's Dermatology in General Medicine, 6th ed.

Such tertiary prevention includes the use of chemical peels, resurfacing techniques like micro-dermabrasion, the use of ablative and non-ablative laser systems, radiofrequency technology, the use of exotoxin Botulinum toxins and soft tissue augmentation, also known as fillers.

For this work he received multiple awards including, the first annual Allergan Award for Aesthetic Achievements, Allergan Award for Pioneering Work in Soft Tissue Augmentation and the American Dermatologic Association Honor Society.