It is unknown if this is the physiological function of Hassall's corpuscles in vivo.

Hassall's corpuscles vary in size with diameters from 20 to more than 100μm, and tend to grow larger with age.

It is known that Hassall's corpuscles are a potent source of the cytokine TSLP.

The function of Hassall's corpuscles is currently unclear, and the absence of this structure in the murine thymus has restricted mechanistic dissection.

Hassall's corpuscles (or thymic corpuscles (bodies)) are structures found in the medulla of the human thymus, formed from eosinophilic type VI epithelial reticular cells arranged concentrically.

Circulating antibodies to the AChR are found in patient with myasthenia gravis, T lymphocyte function is abnormal, and the thymus is enlarged, with prominent germinal centres and Hassall's corpuscles.

Two medical terms are named after Hassall: Hassall's corpuscles, which are spherical bodies in the medulla of the thymus gland, and Hassall-Henle bodies, which are abnormal growths in the Descemet membrane of the eye.