As growth proceeds, the column of cells may divide or give off offshoots, in which case a compound gland is formed.

As a rule, the branches do not unite with one another, but in one instance, the liver, this does occur when a reticulated compound gland is produced.

In compound glands the more typical or secretory epithelium is found forming the terminal portion of each branch, and the uniting portions form ducts and are lined with a less modified type of epithelial cell.