Analysis of banded chromosomes is done at a microscope by a clinical laboratory specialist in cytogenetics (CLSp(CG)).

Images of banded chromosomes with superimposed FITC signal were collected using a MRC Lasersharp 600 confocal imaging system (BioRad).

The purpose of this chapter is to describe some of the available techniques and the ways of utilizing the preparations obtained by them in a variety of applications which range from the simple determination of chromosome counts to the in situ hybridization of gene probes to banded chromosomes.