Aaron's sign is a referred pain felt in the epigastrium upon continuous firm pressure over McBurney's point.

The clinical sign of referred pain in the epigastrium when pressure is applied is also known as Aaron's sign.

Aaron's sign is named for Charles Dettie Aaron, an American gastroenterologist.

Charles Dettie Aaron (8 May 1866 -1951) was an American gastroenterologist from Detroit remembered for Aaron's sign, an indicator of appendicitis.