It is considered a form of 5-alpha-reductase deficiency involving SRD5A2.

Dominican republic: Guevedoche, intersex girls who become boys at puberty, due to 5-alpha-reductase deficiency.

He was born - the product of incest, naturally - with 5-alpha-reductase deficiency, which in the logic of the show means no genitals whatsoever.

Examples of this have occurred in adolescents with several forms of CAH and 5-alpha-reductase deficiency.

Early in the next episode he attributes this to a genetic disorder known as 5-alpha-reductase deficiency that he suffers as a product of incest.

Callie inherited the mutation for a gene that causes 5-alpha-reductase deficiency, which impedes the conversion of testosterone to dihydrotestosterone.

After discovering in his library research 5-alpha-reductase deficiency, an autosomal recessive condition manifested primarily in inbred, insulated population groups, his perception of the novel significantly changed.

The adverse effects of dutasteride are identical to 5-alpha-reductase deficiency, where a developing male child is naturally deficient in 5-alpha reductase type II, and thus unable to synthesize it.

Narrator and protagonist Cal Stephanides (initially called "Callie") is a hermaphrodite man of Greek descent with a condition known as 5-alpha-reductase deficiency, which causes him to have certain feminine traits.

The novel starts with a narration by its protagonist, Cal (his masculine identity), also known as Calliope (feminine): He recounts how 5-alpha-reductase deficiency, a recessive condition, causes him to be born with female characteristics.

In a few parts of the world 5-alpha-reductase deficiency or defects of testosterone synthesis, or even rarer forms of intersex account for a significant portion of cases but these are rare in North America and Europe.

Callie will spend the 1960's and early 70's, the first years of her life, as the relatively unremarkable daughter of an entrepreneurial Greek-American family, only to discover at 14, in the office of a Manhattan physician, that she is a hermaphrodite - or, more precisely, a pseudohermaphrodite, a sufferer of 5-alpha-reductase deficiency syndrome.

Examples of apparent androgen determination of gender identity in XY people with 5-alpha-reductase deficiency in the Dominican Republic had been published, along with reports of masculinized behavior in girls with congenital adrenal hyperplasia (CAH), and unsatisfactory sexual outcomes in adult women with CAH.